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00:00
1.
Positive Affect: Unmet Need of Depression Treatment?
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00:24
2.
《與神同行》 신과함께: 죄와벌
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00:25
3.
Positive Affect: Unmet Need of Depression Treatment?
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04:47
4.
《與神同行》 신과함께: 죄와벌
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05:35
5.
Slide 3
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05:56
6.
World Health Organization
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06:40
7.
Slide 5
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07:15
8.
6
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07:51
9.
Distribution of depression cost is characterized by high indirect costs
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08:14
10.
Impact of depression on life expectancy :Depression kills
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08:30
11.
Non-Suicidal MortalityMortality during 22.6 year follow-up (1.095.338 Swedish young men – 18.3 year old)
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08:45
12.
Slide 12
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09:18
13.
Slide 13
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09:35
14.
憂鬱症治療的 三重難題(地獄)
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10:21
15.
How effective are contemporary antidepressants?
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10:41
16.
How about REMISSION?
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11:06
17.
Treatment Resistant Depression
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11:53
18.
Slide 21
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12:22
19.
Maudsley Staging Model for TRD
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12:29
20.
Repeated inadequate drug trials
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12:59
21.
Initial Inadequate Response
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13:05
22.
DSM : the problem of heterogeneity
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13:49
23.
DSM versus assessment tools :Diversity in depressive symptoms
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15:11
24.
Center for Epidemiological Studies-Depression (CES-D)
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15:38
25.
Lack of positive mood is most specific for depression
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15:52
26.
Dimensions of Major Depressive Disorder
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16:16
27.
Towards a more dimensional approach to MDD ?
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17:57
28.
Factors identified by depressed outpatients as very important in defining remission
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19:05
29.
Is what we measure what matters for patients?
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21:18
30.
Divergence in expectations between physician and patient influences 6 month outcome ( Multivariate - with baseline continuous divergence index )
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21:43
31.
Symptomatic Remission or Functional Remission
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23:06
32.
Symptoms and functioning
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23:46
33.
Clinical factors associated with an improvement of social functioning: the ACTIF study
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24:23
34.
Slide 44
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25:39
35.
Residual symptoms may be the norm
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27:33
36.
Correlation Between Hippocampal Volume and Duration of Untreated Depression
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28:24
37.
Distribution of SDS occupational impairment scores in fully remitted patients
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28:48
38.
沒有回復『生氣勃勃』的remission
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29:11
39.
Dopamine/Serotonin competition/cooperation
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30:48
40.
Slide 52
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31:06
41.
For instance
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31:41
42.
Slide 54
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33:57
43.
Symptom change in CBT
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34:31
44.
Slide 56
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35:32
45.
Conclusions
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36:30
46.
REMAINING CHALLENGE: Remission vs. Recovery
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37:18
47.
我們還有很長的路要走
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37:42
48.
我們還有很長的路要走
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38:03
49.
Slide 94
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38:30
50.
Is what we measure what matters for patients?